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Stacking principles Start with one peptide to establish baseline response before adding others

Topline results from a recent Phase II study 48 in which bremelanotide was co-administered alongside tirzepatide suggest that bremelanotide may help to prevent weight regain, a known issue after tirzepatide treatment ceases 49, 50

From this perspective, the excessive generation of H 2 O 2 induced by CSD in the liver may be preferentially scavenged by GPx, thereby limiting the availability of H 2 O 2 for catalase engagement