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Increasing dosages of antimycin A induced increasing HyPer7 oxidation in the matrix before being released from mitochondria and detectably diffusing into the OMM

Gene ontology (GO) analysis indicated that pathways related to redox regulation were significantly upregulated in senescent HAECs (Fig

HMGB1 secretion, in particular, plays a pivotal role in promoting bone marrow-derived DC recruitment and activation, enhancing antigen presentation and T cellmediated anti-leukemia responses ( in vitro , highlighting the therapeutic potential of reactivating the ferroptosisHMGB1 axis in resistant CML (Sun et al., 2023)