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Description

The drug has shown good tolerability, with mild side effects such as drowsiness, rash, and dizziness, but no significant adverse events in most patients

Glutathione is often called the bodys master antioxidant, and for good reason

To address this, we generated an in vitro model of CMT2/SORD MNs by reprogramming carrier and patient fibroblasts ( SORD c.757delG/wt , SORD wt/c.316_425+165del , and SORD c.757delG/c.316_425+165del , indicated as SORD +/- #1, SORD +/- #2 and SORD -/- #1, respectively) into induced pluripotent stem cells (iPSCs)