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In vitro and in vivo studies showed an increased antileukemic effect for the combination of DFO and cytarabine (136), DFX and decitabine (137) as well as DFO and doxorubicin (138)

The JNK pathway is known to regulate mGluR-dependent gene transcription (Wang and Zhuo, 2012)

In a vicious circle, feeding itself, SARS-CoV-2 may aggravate the evolution of atherosclerosis as a result of excessive and aberrant plasmatic concentration of cytokines (Vinciguerra et al., 2020

In addition to its direct antimycobacterial activity, BA promotes bacterial clearance during mycobacterial infection through the activation of the NRF2KEAP1 and HO-1 signaling pathways ( Figure 3 )