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For PD, APS protect neurons and stabilize mitochondrial function by inhibiting ROS production and promoting autophagy through the PI3K/AKT/mTOR pathway

(2017), age-adjusted hazard ratios for the shortest LTL quintile compared to the longest were found to be higher by 23, 29, and 10% for all-cause mortality, cardiovascular mortality, and cancer mortality, respectively

By inhibiting key muscle synthesis pathways (including PI3K/AKT/mTOR), cancer treatments like sorafenib cause muscular atrophy [55]

CHCHD2: coiled-coil-helix-coiled-coil-helix domain containing 2 EGCG is a promising drug for neurodegenerative diseases due to its ability to prevent and mitigate protein aggregation through various mechanisms