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This directly indicated increased tolerance to virus infection stress could be an effect of co-involvement of GSH and NPR1 which was observed in tolerant interaction of tobacco with other types of pathogens ( Nicotiana tabacum ) and in constitutive GSH synthesis during potato virus X (PVX) accumulation control in Nicotiana benthamiana ( NTN and TuMV on susceptible and resistant (with hypersensitive response or hypersensitive-like, HR or HR-like) respectively on potato and rbohF and rbohD/f mutants of Arabidopsis ( Figure 2 )

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