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Dynamic multistage nanozyme hydrogel reprograms diabetic wound microenvironment: synergistic oxidative stress alleviation and mitochondrial restoration

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This process is not only time-consuming but also high-risk and expensive, with the average cost of developing a new drug ranging between $100 million and $2 billion, and the timeline stretching from 10 to 17 years

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Since the nitrogenase activity of Klebsiella species is known to be tolerant of oxygen to some extent 28 , NG13 was cultured microaerobically in medium containing 100 mg L 1 yeast extract in a non-hermetic tube without shaking

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