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SubQ vs IM vs IV: three routes, three experiences SubQ (subcutaneous) : injected into the fatty layer under the skin

No established upper limit exists because excess b12 excretes through kidneys without causing harm

For severe deficiencies, especially those with neurological symptoms, a full resolution of symptoms might take several weeks or even months of consistent treatment

A daily dose of 8 mg for men and 18 mg for women is generally sufficient for adults but if you have an iron deficiency a higher dose may be recommended