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One study found that a regimen of 0.5mg vaginal estriol daily for 2 to 3 weeks followed by twice weekly administration for a period of 2 years did not result in endometrial proliferation.14 Many of the studies currently available evaluate estriol specifically via the vaginal route, though, it is sometimes compounded via the oral or transdermal routes as well

These include: Fatigue Irritability Mouth ulcers Constipation A yellow tinge to the skin Sore tongue Pins and needles Behavioural changes Memory problems If you follow a vegetarian or vegan diet, it is particularly important to take note of these symptoms

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These are prescribed for symptomatic relief as they reduce the inflammatory intermediates in the body like prostaglandins and leukotrienes to reduce inflammation