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Spermidine/spermine N1-acetyltransferase 1 (SSAT) initiates polyamine catabolism, which decreases the cellular content of polyamines through transferring the acetyl group of acetyl-CoA to either spermidine or spermine, which can be oxidized by peroxisomal enzyme polyamine oxidase (PAOX)

Arnman R, Olsson R

Although SNO modification is less common compared to other modifications such as phosphorylation [59], it still widely occurs in various proteins, including microtubules, apoptotic proteins, metabolic proteins, redox proteins, vesicles, enzymes, and signal pathway proteins

Secondary outcomes including mortality from cardiometabolic causes, including cardiovascular, neurovascular, and diabetes-related events, were similarly analyzed