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doi: 10.1016/j.ijbiomac.2020.10.127 112 BenalayaIAlvesGLopesJSilvaLR

The cancer epigenome: exploiting its vulnerabilities for immunotherapy

To illustrate, radiotherapy results in mitochondrial damage and mitophagy, which releases free fatty acids and increases lipid peroxidation, thereby inducing ferroptosis in tumor cells [137]