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10.1097/cad.0b013e3283355227 9 ChengZ.KangC.CheS.SuJ.SunQ.GeT.et al (2022)

COMMD5 loss leads to excessive autophagy with inefficient degradation, resulting in ROS accumulation, mitochondrial failure, and cell death (184)

Goblet cell hyperplasia, metaplasia, and excessive mucus production are key pathological features of chronic airway diseases such as chronic obstructive bronchitis (part of COPD) and CF