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Similar content being viewed by others Introduction Despite the variability in oncogenic factors across different cancers, there are well-established fundamental hallmarks that characterize cancerous tissues

Large-scale clinical studies have systematically investigated circulating markers reflecting BBB dysfunction and vascular pathology

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The common drivers: A weak or loose LES A hiatal hernia (part of the stomach pushing up through the diaphragm) Eating large meals, especially within three hours of bed Excess abdominal weight pressing on the stomach Smoking (which relaxes the LES) Pregnancy Certain medications, including some blood pressure drugs and asthma inhalers I tell patients this all the time: if you have reflux and youve never had a proper workup, youre treating a symptom and ignoring the engine