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Seizure medications such as phenytoin and phenobarbital, as well as diabetes medications like metformin, can lower B12 levels over time

Anti-GAD65Ab-associated CAs affect mostly women in their 5060s and exhibit subacute or chronic CAs, which are sometimes associated with SPS or epilepsy [76]

Biochemically, this phase is associated with reduced activity of HIF- and upregulation of Sirtuin activity

We present the case of 43-year-old man, previously in good health, who experienced severe ADRs 5 days after completion of levofloxacin treatment, and was finally diagnosed with fluoroquinolone-associated disability (FQAD)