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In this study, we conducted an untargeted NMR-based metabolomics analysis of serum samples collected from individuals with epilepsy, both at baseline state and immediately following seizure episodes, and compared them with samples from healthy controls

These gaps highlight the need for future research to move beyond descriptive mechanisms toward systematic dissection of pathway crosstalk, cell type-specific functions, and clinical validation

Studies have demonstrated that the polarization of macrophages is controlled by multiple metabolic pathways, such as glycolysis, the pentose phosphate pathway, fatty acid oxidation, sphingolipid metabolism, the tricarboxylic acid cycle, and arginine metabolism

Unlike traditional anti-inflammatories that only suppress symptoms, these supplements for swelling actively promote healing by targeting specific biological pathways