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ADHD as a circadian rhythm disorder: evidence and implications for chronotherapy

composition of the present invention may be in a form dissolved in water or in a lyophilized form with a crystallizing solute such as mannitol

[13] Moreover, they are more likely to be deficient in folate, B6, and B12, and may require activated versions of these nutrients to address these deficiencies

In humans, as in other vertebrates, these changes serve not only to ensure survival but also, in many cases, to facilitate successful establishment in such environments