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C.LiuD.LorenziM

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The NADPH is produced in the pentose phosphate pathway, one of the cell's central metabolic loops

The system locks a drug (e.g., the fluorophore RhB or the anticancer drug camptothecin CPT) in the pore via a nucleic acid hairpin structure and catalyzes the unlocking of the hairpin to release the drug using nucleic acid exonuclease or cutase