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The results indicated that dental pulp stem cell injections at a dose of 1 10 7 were more effective in patients with stage III periodontitis (attachment loss 5 mm) compared to those with stage II periodontitis (attachment loss 25)

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gradual dose escalation helps minimize these effects [1][3]

Febuxostat is approved by the FDA to start at 40mg daily, and if the uric acid has not reached goal (less than 6.0mg/dL) after two weeks of treatment the dose can be increased to 80mg daily