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The active conformation of -arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of -arrestins1 and -2

Fue descubierto en 1973 por Loren Pickart durante su trabajo doctoral en la University of California, San Francisco (UCSF)

T cells cultured within high-density collagen matrices exhibit diminished cytotoxic activity and reduced secretion of IFN-, a pivotal cytokine crucial for mounting an effective immune response (74)

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