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Recently, calcium channels namely transient receptor potential (TRP) superfamily, including members of the subfamilies A (TRAP1), M (TRPM2 and 7), and V (TRPV1 and 4), have demonstrated to play a role in the nociception mediated by sensory neurons

To date, most clinical studies have been of short duration (412 weeks), and long-term safety data in neurodegenerative populations are lacking ( 11 Conclusion Astaxanthin has emerged as a uniquely versatile carotenoid with potent antioxidant, anti-inflammatory, and mitochondrial-supporting properties that distinguish it from many conventional antioxidants

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