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It is essential to remember that this process is multifactorial since ALA is present in the diet (as the biologically active form R-ALA), dietary supplements, and drugs

liver being among organs with the highest content (56)

This research was supported in part by an award from the All of Us Research Program to the National Alliance for Hispanic Health, funded by the Division of Engagement and Outreach, All of Us Research Program, National Institutes of Health (Award Number OT2OD025277), and the Lucy Delgado Fund of the Healthy Americas Foundation

Before entering the GSL core biosynthetic pathway, Met undergoes chain elongation process in chloroplasts, which is similar to the conversion of the branched-chain amino acid Val to Leu in primary metabolism