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The efficacy of valproate in reducing the incidence of complex partial seizures (CPS) that occur in isolation or in association with other seizure types was established in two controlled trials

For instance, KG, also known as 2-oxoglutarate (2OG), is a co-substrate for KGDDs that include DNA and histone demethylases 2

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Throughout the set of experiments, high-cell density membrane reactors were run at different dilution rates and growing and resting periods were alternated