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This not only causes great difficulties for patients to take care of themselves in daily life but also brings a heavy burden to families and society (O'shea et al., 2017)

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Both DSIP and DSIP-CBBBP treatments increase serotonin levels significantly, suggesting their effectiveness in improving sleep effects, while CBBBP alone shows no significant impact on serum levels of melatonin, serotonin, dopamine, and glutamate

These results suggested that RPL15 could mediate the activation of the Wnt/-catenin signaling pathway