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Lynch's How-to Sauna Guide

In this model, cells are incubated in a glucose-free medium under deoxygenated atmosphere in order to mimic the conditions occurring during an ischemic stroke (Tasca et al., 2015)

Additionally, ALA enhanced the level of PPAR-, facilitated the nuclear translocation of Nrf2 and inhibited NF-B activation, leading to increased antioxidant levels and reduced inflammation