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This vital antioxidant is naturally derived from the amino acids L-glutamic acid, L-cysteine and glycine

Furthermore, DKK-1 teams up with the ovarian-tumor ubiquitin binder OTUB1 to lock SLC7A11 into an active, long-lived state, thereby hampering ferroptosis (Wu et al., 2022

This localized depletion of the brain's master antioxidant is accompanied by abnormally high levels of ventricular lactate and free radicals, indicating that the brain is suffering from severe oxidative stress and impaired cellular energy metabolism

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