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10.1097/00003086-199302000-00042 58 KawaiT.MiekiA.OhnoY.UmemuraM.KataokaH.KuritaS.et al (1993)

Small, repeat doses work best

The mechanism of thiosulfate protection appeared to be extremely rapid formation of thiocyanate in the central compartment, which therefore limited the amount of cyanide distributed to sites of toxicity

Methylcobalamin and hydroxocobalamin tend to be better tolerated than cyanocobalamin, which may cause more allergic or dermatological reactions in sensitive individuals