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Of the 8 patients who received combination therapy with a PD-1 inhibitor and a CTLA-4 inhibitor, 2 (25%) had an immune-related adverse event, with 1 of these patients having 3 immune-related adverse events

6o) which inhibits the ATP synthase, and thus, suggests that ADP phosphorylation capacity is unchanged

The first was substances with enough of a safety track record that the agency felt comfortable letting compounders use them while the final list was assembled