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Healthy growing follicles exhibit resistance to granulosa cells apoptosis, whereas in early atretic follicles, apoptosis begins in the inner granulosa cells layer and progressively affects most granulosa cells, leading to follicular atresia (Tilly et al., 1991)

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Int J Biol Macromol 98:169181 Lee J-S, Kim H-G, Han J-M, Kim D-W, Yi M-H, Son S-W, Kim Y-A, Lee J-S, Choi M-K, Son C-G (2014) Ethanol extract of astragali Radix and salviae miltiorrhizae radix, myelophil, exerts anti-amnesic effect in a mouse model of scopolamine-induced memory deficits