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Does the lipid bilayer orchestrate access and binding of ligands to transmembrane orthosteric/allosteric sites of G protein-coupled receptors

Meanwhile, peptides have gained attention in recent years due to their non-toxic and effective properties, attracting significant interest from researchers 25,29,30

Modification of endogenous JA levels in plants appeared to be a promising method of providing protection against numerous abiotic stresses, including salinity, heat, drought, and metal toxicity 18,19

The principle behind this connection may be due to the role of extracellular HMGB1 in angiogenesis, cell migration, and macrophages recruitment, which could contribute to tumor growth and metastasis