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While a substantial portion of Glu in the synaptic cleft is cleared by GLAST and neuronal GLT-1, there remains an excess of Glu within the synaptic cleft, influencing the postsynaptic neuronal excitability

We found that the cells form the TARDBP family have an impaired defense system against oxidative stress, with lower glutathione levels respect to the unrelated CTRLs, suggesting reduced abilities to cope with oxidative stress, which may account for the increase in ROS levels, despite the upregulation of SOD2 expression in patients cells

Similar content being viewed by others Introduction Crohns disease (CD), a form of inflammatory bowel disease (IBD), is characterized by inflammation and ulceration in the gastrointestinal tract

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