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Description

In research literature, this pairing is often examined for its theoretical ability to elevate growth hormone and downstream insulin-like growth factor-1 (IGF-1) levels while maintaining physiological rhythms

This process requires the binding of HP1 proteins and consequent recruitment of the H3K9me1/2 HKMTs G9A and GLP and the H3K9me3 HKMT SUV39H1, which reinforce the silencing of genes located within the constitutive heterochomatin and initiate the repression of genes previously embedded in euchromatin [53]