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Suzuki N, Koussevitzky S, Mittler R, Miller G (2012) ROS and redox signalling in the response of plants to abiotic stress

That is not a reason to dismiss the animal data, but it is a reason to frame it correctly

A major topic in our research group is the role sex hormones play in the risk of Alzheimer's disease and how sex hormones can affect the disease profile

With cuprizone exposure, the recruitment of T-cells to the lesion site [70] may result from the decreased BBB integrity induced by cuprizone [75, 76] Cuprizone toxicity produces profound demyelination in the white and grey matter of the brain that mirrors sites of MS pathology [46]