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Safety Comparison Summary# Practical Considerations# Availability and Formulation# Both Dihexa and PE-22-28 are available only as research chemicals from peptide suppliers

*Correspondence: Zhigang Ren, [email protected] Yu, [email protected] These authors have contributed equally to this work This article was submitted to Signaling, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers