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Penpulimab (AntiPD-1) for Recurrent or Metastatic Non-Keratinizing Nasopharyngeal Carcinoma FDA Approval Date: April 23, 2025 Penpulimab, an Fc-engineered PD-1 inhibitor, was approved with platinum-gemcitabine chemotherapy for first-line treatment of recurrent or metastatic non-keratinizing NPC, and as monotherapy after platinum-based therapy