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Allergic reaction: Serious allergic reactions have been reported

The practical approach is to use a lower concentration (5mg/mL) for the first 8-12 weeks when precision matters most during introduction, then switch to a higher concentration (10-20mg/mL) as you move into higher doses

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In the CY 2011 PFS final rule (75 FR 73461 through 73465), we addressed situations in which ASP data for some, but not all, NDCs in a multiple source drug billing and payment code are not available for the calculation of an ASP payment limit (for example, if a manufacturer's entire submission of data was not received or manufacturer's ASP data for specific NDCs was not reported)