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Anti-tumor pharmacology of natural products targeting mitosis

Prevalence and correlates of muscle dysmorphia in a sample of boys and men in Canada and the United States

Then, the rate-limiting enzyme in arginine synthesis, argininosuccinate synthetase 1 (ASS1), catalyzes the conversion of citrulline and aspartate into argininosuccinate, which is then cleaved into arginine and fumarate by argininosuccinate lyase (ASL) (Figure 1)