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The study conducted by Pevec et al

Scaled up for a human weight of 70 kg, this would be 35 micrograms in a human [52]

Sustained microglial activation leads to the release of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which exacerbate neuronal injury and amplify amyloid and tau pathology (Kaur et al., 2019)