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Diagnosis In contrast to fibrosarcomas in other areas, FISS have different histological characteristics with typical perivascular infiltration of lymphocytes and macrophages at the tumour periphery, a central area of necrosis, inflammation and local infiltration of tumour cells (Fig

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Corticosteroids, such as prednisolone, beclomethasone and budesonide, are broad-spectrum anti-inflammatory agents that work by modulating several inflammatory pathways[28,29]

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