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In addition, based on clinical research, it is important to identify the syndromes and conditions that can benefit from the KD-based therapies, contraindications for use, KD variants with good effectiveness and tolerability, and factors and biomarkers that can predict KD-related outcomes, which may collectively guide the clinical utilization of the KD in different diseases

Alternatively, water intake can be kept relatively constant (with the exception of a few hours before competing to prevent any abdominal distention) to minimize the variables being manipulated

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