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Balanced diet: Include natural or fortified B12 sources regularly

Delta sleep-inducing peptide crosses the blood-brain-barrier in dogs: some correlations with protein binding

IL-2/IL-2 antibody immune complex regulates HSV-induced inflammation through induction of IL-2 receptor alpha, beta, and gamma in a mouse model

B12 is also used by the immune system - so not having enough leads to higher rates of infection but also means that some of the responses that we associate with being unwell (which are actually the immune system fighting the infection) - like runny nose, rashes - can also seem to go into overdrive for a while