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These effects are often transient and tend to subside as the body adapts or doses are titrated

Furthermore, upon evaluating the link between the MTHFR A1298C variant and PD, an increased risk of PD was observed in association with both the dominant and heterozygous models (Liu et al., 2018)

Previous studies have applied the standard Mini-International Neuropsychiatric Interview or the Hamilton Depression Rating Scale and the Beck Depression Inventory for evaluating the mood state of GD patients, which can be potential methods for assessing the patients' mental state (182)