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Description

Cloning and chromosomal mapping of the human non-functional gene forl-gulono-y-lactone oxidase, the enzyme forl-ascorbic acid biosynthesis missing in man

In practice, the challenge is rarely just "can GSH react?"it is whether the conjugation route will give the desired attachment site, manageable impurity profile, acceptable stability, and data that clearly distinguish the target product from free glutathione, oxidized material, and positional isomers