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Analysis of the variant representation in treated vs untreated samples would allow us to determine variants that were depleted in the treated population as compared to the control (Fig

Active DNA demethylation occurs under the catalysis by TET proteins, which sequentially oxidize 5-methylcytosine (5mC) to 5hmC, then to 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) [38, 104, 126, 147]

In this area, co-administration of Lactobacillus gasseri and tumor necrosis factor-alpha inhibitor infliximab improved colitis in mice [103]

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