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Minor differences in the appearance of the lyophilized peptide between production lots are normal and generally reflect variations in freeze-drying conditions rather than differences in peptide identity or analytical purity

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In such cases, the subject still technically has PD, but the quality of life of the subject is significantly improved because the progression of symptoms is slowed, or even stopped (arrested) at an earlier stage than would be possible without administration of the HGF mimic(s), e.g

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OBrien JT, Ames D, Schweitzer I et al (1996) Enhanced adrenal sensitivity to adrenocorticotrophic hormone (ACTH) is evidence of HPA axis hyperactivity in Alzheimers disease

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