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J Hematol Oncol 15 , 65 (2022)

The glutaredoxin (Grx)/GSH/GSH reductase (Gor) system catalyzes specific de-glutathionylation of S -glutathionylated proteins (Fernandes and Holmgren, 2004

At the same time, they strongly inhibit active oxygen and scavenge free radicals, and can reduce lipid peroxidation caused by iron overload, which results in cell damage