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Consistently, co-administration of the RAGE inhibitor FPS-ZM1 effectively suppressed ferroptosis and enhanced Nrf2 activity in CLP-induced mice

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3.4 C-PC and CDDP Induce Cellular Morphological Changes and DNA Fragmentation in GBM Cells To evaluate the cytotoxic mechanisms of C-PC individually and in combination with CDDP, we examined the morphology of GBM cells using light microscopy (Fig