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Step 3: Optimization phase (weeks 3-8) Based on assessment results, establish your working protocol: Dose: Your minimum effective dose (typically 75-200mcg) Frequency: 3-5 times weekly based on tolerance observations Timing: Your optimal pre-bedtime window Track results weekly and make minor adjustments as needed

If jitteriness is accompanied by chest pain, severe palpitations, difficulty breathing, or loss of consciousness, seek immediate medical attention by calling 999 or attending A&E

Others use varying preservative systems

Elevation works with gravity to help fluid that would otherwise accumulate in the knee flow back to the central circulation