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Importantly, the prevalence is even higher when asymptomatic neuropathy is included, with 45% of patients with T2DM and 54% of those with T1DM developing neuropathy 20

de Bruin JP, Dorland M, Spek ER, Posthuma G, van Haaften M, Looman CW, et al

J Control Release 329:136147 Cuccioloni M, Bonfili L, Mozzicafreddo M, Cecarini V, Pettinari R, Condello F, Pettinari C, Marchetti F, Angeletti M, Eleuteri AM (2016) A ruthenium derivative of quercetin with enhanced cholesterol-lowering activity