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[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Zhao R., Bruning E., Rossetti D., Starcher B., Seiberg M., Iotsova-Stone V

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This dysregulation is secondary to mutations in elements of the pathway that include the APC gene (adenomatous polyposis coli), -catenin, or other elements, which make the pathway to be constitutively active and has oncogenic consequences [118, 119]