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alternatively, it may arise as a downstream consequence, driven or amplified by ongoing neuroinflammation (e.g., iron sequestration by activated microglia) and proteinopathy (e.g., iron chelation by A/tau), as indicated by clinicopathological studies

10.1093/ajcp/56.2.137 56 NiiharaY.MillerS

Zhang Q, Lei Y-H, Zhou J-P, Hou Y-Y, Wan Z, Wang H-L, et al

They say, "It's a little bit better but it's gone pretty quickly," and you'll tell them, "Yes, that's right, your body took that B12 in and it's not there anymore